Tasirin Kariya naIlimin Kimiyyar Fataakan Fata
Glandan sebaceous suna fitar da lipids, waɗanda ƙwayoyin cuta ke narkewa don samar da fim ɗin lipid mai emulsified. Waɗannan fina-finan lipid suna ɗauke da fatty acids kyauta, wanda aka fi sani da fina-finan acid, waɗanda zasu iya kawar da abubuwan alkaline da suka gurɓata a fata da kuma hana ƙwayoyin cuta na waje (ƙwayoyin cuta masu wucewa). , fungi da sauran ƙwayoyin cuta masu cutarwa suna girma, don haka aikin farko na flora na fata na yau da kullun shine muhimmin tasiri na kariya.
Kutsewar fata da abubuwan da ke cikinta, gami da glandar gumi (gumin gumi), glandar sebaceous, da kuma gashin gashi, suna da nasu nau'in flora na musamman. Glandar sebaceous suna haɗa gashin gashi don samar da follicular sebaceous unit, wanda ke fitar da wani sinadari mai yawa da ake kira sebum. Sebum wani fim ne mai kariya daga ruwa wanda ke karewa da kuma shafa mai a fata da gashi kuma yana aiki a matsayin garkuwar kashe ƙwayoyin cuta. Glandar sebaceous suna da ƙarancin hypoxic, suna tallafawa ci gaban ƙwayoyin cuta masu hana ƙwayoyin cuta kamar suP. kuraje, wanda ke ɗauke da P. acnes lipase wanda ke lalata sebum, yana rage yawan triglycerides a cikin sebum, kuma yana fitar da free fatty acids. Kwayoyin cuta na iya manne wa waɗannan free fatty acids, waɗanda ke taimakawa wajen bayyana yadda P. acnes ke mamaye glandar sebaceous, kuma waɗannan free fatty acids suma suna taimakawa wajen ƙara yawan acidity na saman fata (pH na 5). Yawancin ƙwayoyin cuta masu cutarwa, kamar Staphylococcus aureus da Streptococcus pyogenes, ana hana su a cikin yanayi mai acidic kuma don haka suna da kyau ga haɓakar coagulase-negative staphylococci da coryneform bacteria. Duk da haka, toshewar fata yana haifar da ƙaruwa a cikin pH wanda zai taimaka wa ci gaban S. aureus da S. pyogenes. Saboda mutane suna samar da ƙarin sebum triglycerides fiye da sauran dabbobi, ƙarin P. acnes suna mamaye fatar ɗan adam.
Lokacin Saƙo: Yuni-27-2022
