Kayan kwalliya na farin gashi da kumaLauniMetabolism
An raba sinadarin Melanin zuwa yanayi daban-daban. Masana kimiyya sun yi imanin cewa yana yiwuwa a yi nazarin sinadaran da ke ƙara farin jini da kuma yin aiki na tsawon lokaci daban-daban na metabolism.
(1) Matakin farko na haɗa melanin
① Tsangwama ga rubutun da/ko glycosylation na tyrosinase; ② Hana masu kula da tsarin samar da tyrosinase; ③ Kula da tyrosinase bayan an rubuta shi.
(2) Lokacin haɗa Melanin
A matsayin babban enzyme da enzyme mai iyakance rate don haɗa melanin, masu hana tyrosinase sune babban alkiblar bincike da haɓakawa a halin yanzu. Tunda yawancin sinadaran fari kamar phenol da catechol sun yi kama da tyrosine da dopa a tsarin, ana rarraba sinadaran fari da aka tantance a matsayin masu hana tyrosinase marasa gasa ko masu gasa.
(3) Matakin ƙarshe na haɗa melanin
①Yana hana canja wurin melanosome; abubuwa masu tasirin hana serine protease, kamar rwj-50353, suna guje wa launin epidermal da UBV ke haifarwa gaba ɗaya; mai hana trypsin na waken soya yana da tasirin farin fata a bayyane amma ba shi da tasiri kan gubar ƙwayoyin pigment; Niacinamide, na iya hana watsa melanocytes tsakanin melanocytes da keratinocytes; ② Yaɗuwar Melanin da metabolism, α-hydroxy acid, free fatty acid da retinoic acid, suna ƙarfafa sabunta ƙwayoyin halitta da kuma haɓaka cire melaninocytes na melanin.
Ya kamata a lura cewa bincike da amfani da abubuwan da ke ƙara farin jini bisa ga metabolism na melanin da ke sama ba su dace da rigakafi da maganin plaques na tsufa ba. Tunda hanyar samar da plaque na tsufa tana da alaƙa da samuwar lipofuscin, ana amfani da abubuwa masu aiki na hana oxidative don jinkirtawa da kuma mayar da plaques na tsufa.
Lokacin Saƙo: Yuli-29-2022
